Sweating the details: What really drives eccrine output during exercise-heat stress

摘要

Copious sweating observed during passive or exercise-induced heat stress (exercise-heat stress) is the primary outcome of the sophisticated eccrine-dependent cooling system that has evolved in humans. One can speculate as to why sweating, with its large ability to liberate heat (SSOkcalT1), would be advantageous for a 'naked ape' ambulating in a warm savanna environment. Despite this grand role of sweating in human thermoregulation and evolution, it is humbling how little we know of its control and regulation. Recent work is beginning to detect the precise brain areas involved (Shafton & McAllen, 2013), but imprecise systemic factors are reported in the literature to be the primary drivers of eccrine sweating.