There is an interesting difference between experimental investigations and clinical practice. While experiments typically report changes in variables following a given intervention, a diagnosis is based on observing manifestation(s) of a disease or on interpretation of one or, more likely, several measured variables. In short, the clinician observes the 'y-axis' and has to derive the 'x-axis' from it. Yet, it is important that a physiological text accurately describes the typical deviations of variables associated with the intervention. Furthermore, accuracy becomes vital when the text addresses responses to a life-threatening circumstance like hypovolaemic shock caused by not only haemorrhage but also by, e.g., postural stress in the heat and lung recruitment manoeuvres by manual lung inflation, of relevance for intensive care medicine.
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