Resveratrol as a supplement to exercise training: Friend or foe?

摘要

We recently read with great interest the manuscript by Gliemann et al. (2013) entitled 'Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men' as well as the Editorial response by Smoliga & Blanchard (2013). In the study by Gliemann et al. (2013), the authors implemented an 8 week exercise-training intervention among sedentary, but otherwise healthy older men [n = 27; 65 +- 1 year old (mean +- SEM)] in concert with 250 mg day~-1 of oral trans-resveratrol supplementation (n- 14) or placebo (n = 13). The authors noted statistically significant improvements in several cardiovascular outcomes (e.g. mean arterial blood pressure, cholesterol and maximal oxygen uptake) among the placebo group that were not observed among the resveratrol group. Based on these findings, it was concluded that 'resveratrol blunts the positive effects of exercise'.