Breast density, assessed by mammography and expressed as a percentage of the mammogram occupied by radiologically dense fibroglandular tissue, is a strong predictor of the failure of mammographic screening to detect breast cancer lesions. That this correlation is not entirely attributable to the physical masking of breast lesions by dense tissue has become increasingly clear over the past decade; rather, analyses of breast-tissue composition have shown that breast density is an independent risk factor for breast cancer.
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