Clinical and Radiographic Efficacy of Sarilumab Plus Methotrexate in Biologic-Experienced and Biologic-Naive Patients with Rheumatoid Arthritis in a Phase 3, Randomized, Double-blind, Placebo-Controlled Study

Fiore Stefano; Genovese Mark; Fan Chunpeng; Decktor Dennis; Fleischmann Roy

首页> 外文期刊>The Journal of rheumatology >Clinical and Radiographic Efficacy of Sarilumab Plus Methotrexate in Biologic-Experienced and Biologic-Naive Patients with Rheumatoid Arthritis in a Phase 3, Randomized, Double-blind, Placebo-Controlled Study

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Clinical and Radiographic Efficacy of Sarilumab Plus Methotrexate in Biologic-Experienced and Biologic-Naive Patients with Rheumatoid Arthritis in a Phase 3, Randomized, Double-blind, Placebo-Controlled Study

机译：Sarilumab加甲氨蝶呤在有生物学经验和未接受过生物治疗的类风湿关节炎患者的临床和影像学疗效，一项三期，随机，双盲，安慰剂对照研究中

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《The Journal of rheumatology》 |2016年第6期|共1页
作者
Fiore Stefano; Genovese Mark; Fan Chunpeng; Decktor Dennis; Fleischmann Roy;
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中图分类免疫性疾病;
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1. Clinical and Radiographic Efficacy of Sarilumab Plus Methotrexate in Biologic-Experienced and Biologic-Naive Patients with Rheumatoid Arthritis in a Phase 3, Randomized, Double-blind, Placebo-Controlled Study [J] . Fiore Stefano, Genovese Mark, Fan Chunpeng, The Journal of rheumatology . 2016,第6期

机译：Sarilumab加甲氨蝶呤在有生物学经验和未接受过生物治疗的类风湿关节炎患者的临床和影像学疗效，一项三期，随机，双盲，安慰剂对照研究中
2. Maintenance of Clinical and Radiographic Benefit With Intravenous Golimumab Therapy in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy: Week-112 Efficacy and Safety Results of the Open-Label Long-Term Extension of a Phase III, Double-Blind, Randomized, Placebo-Controlled Trial [J] . Bingham Clifton O. III, Mendelsohn Alan M., Kim Lilianne, Arthritis care & research . 2015,第12期

机译：尽管采用甲氨蝶呤治疗，但活动性类风湿关节炎患者采用静脉Golimumab治疗维持临床和放射学获益：III期，双盲，随机，安慰剂对照的开放标签长期延长的112周疗效和安全性结果试用版
3. Effect of denosumab on Japanese patients with rheumatoid arthritis: a dose-response study of AMG 162 (Denosumab) in patients with RheumatoId arthritis on methotrexate to Validate inhibitory effect on bone Erosion (DRIVE)-a 12-month, multicentre, randomised, double-blind, placebo-controlled, phase II clinical trial [J] . Takeuchi Tsutomu, Tanaka Yoshiya, Ishiguro Naoki, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2016,第6期

机译：地诺单抗对日本类风湿性关节炎患者的影响：甲氨蝶呤风湿性关节炎患者中AMG 162（Denosumab）的剂量反应研究，以验证其对骨侵蚀（DRIVE）的抑制作用-12个月，多中心，随机，双盲目，安慰剂对照，II期临床试验
4. A DOUBLE-BLIND RANDOMIZED PLACEBO-CONTROLLED CLINICAL TRIAL TO INVESTIGATE THE EFFICACY OF TIAMULIN IN THE CONTROL OF PORCINE PROLIFERATIVE ENTEROPATHY (PPE) AND PORCINE COLONIC SPIROCHAETOSIS (PCS) UNDER FIELD CONDITIONS [C] . J. Haugegaard, K. Moller, T.K. Jensen, Congress of the International Pig Veterinary Society . 2000

机译：一种双盲随机安慰剂对照临床试验，探讨硫霉素在野生植物中猪增殖肠病（PPE）和猪结肠螺旋肌肤症（PCS）的疗效
5. A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil (Eicosapentaenoic Acid and Docosahexaenoic Acid) on Lung and Systemic Inflammation in Patients with Acute Lung Injury. [D] . Stapleton, Renee Doney. 2010

机译：鱼油（二十碳五烯酸和二十二碳六烯酸）对急性肺损伤患者的肺和全身炎症的II期，随机，双盲，安慰剂对照试验。
6. Extended report: Effect of denosumab on Japanese patients with rheumatoid arthritis: a dose–response study of AMG 162 (Denosumab) in patients with RheumatoId arthritis on methotrexate to Validate inhibitory effect on bone Erosion (DRIVE)—a 12-month multicentre randomised double-blind placebo-controlled phase II clinical trial [O] . Tsutomu Takeuchi, Yoshiya Tanaka, Naoki Ishiguro, -1

机译：扩展报告：地诺单抗对日本类风湿关节炎患者的影响：风湿性关节炎甲氨蝶呤患者中AMG 162（Denosumab）的剂量反应研究以验证其对骨侵蚀（DRIVE）的抑制作用-一项为期12个月的多中心随机研究双盲安慰剂对照的II期临床试验
7. Faculty Opinions recommendation of Effect of denosumab on Japanese patients with rheumatoid arthritis: a dose-response study of AMG 162 (Denosumab) in patients with RheumatoId arthritis on methotrexate to Validate inhibitory effect on bone Erosion (DRIVE)-a 12-month, multicentre, randomised, double-blind, placebo-controlled, phase II clinical trial. [O] . Sakae Tanaka 2019

机译：教师意见Denosumab对日本类风湿性关节炎患者的建议：AMG 162（Denosumab）对类风湿性关节炎患者对甲氨蝶呤抑制骨侵蚀（驱动）-A的抑制作用（驱动）-A 12个月，Multicentre的抑制作用的剂量 - 反应研究。随机，双盲，安慰剂控制，II期临床试验。

Clinical and Radiographic Efficacy of Sarilumab Plus Methotrexate in Biologic-Experienced and Biologic-Naive Patients with Rheumatoid Arthritis in a Phase 3, Randomized, Double-blind, Placebo-Controlled Study

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