Upregulation of Thrombospondin 1 Expression in Synovial Tissues and Plasma of Rheumatoid Arthritis: Role of Transforming Growth Factor-beta 1 toward Fibroblast-like Synovial Cells

Suzuki Takahisa; Iwamoto Naoki; Yamasaki Satoshi; Nishino Ayako; Nakashima Yoshikazu; Horai Yoshiro; Kawashiri Shin-ya; Ichinose Kunihiro; Arima Kazuhiko; Tamai Mami; Nakamura Hideki; Origuchi Tomoki; Miyamoto Chikara; Osaki Makoto; Ohyama Kaname; Kuroda Naotaka; Kawakami Atsushi

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Upregulation of Thrombospondin 1 Expression in Synovial Tissues and Plasma of Rheumatoid Arthritis: Role of Transforming Growth Factor-beta 1 toward Fibroblast-like Synovial Cells

机译：类风湿关节炎滑膜组织和血浆中血小板反应蛋白1表达的上调：转化生长因子-β1向成纤维细胞样滑膜细胞的作用。

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Objective. To investigate the role of thrombospondin 1 (TSP-1) in RA.

机译：目的。调查血小板反应蛋白1（TSP-1）在RA中的作用。

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来源
《The Journal of rheumatology》 |2015年第6期|共5页
作者
Suzuki Takahisa; Iwamoto Naoki; Yamasaki Satoshi; Nishino Ayako; Nakashima Yoshikazu; Horai Yoshiro; Kawashiri Shin-ya; Ichinose Kunihiro; Arima Kazuhiko; Tamai Mami; Nakamura Hideki; Origuchi Tomoki; Miyamoto Chikara; Osaki Makoto; Ohyama Kaname; Kuroda Naotaka; Kawakami Atsushi;
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正文语种 eng
中图分类免疫性疾病;
关键词
RHEUMATOID ARTHRITIS; FIBROBLAST-LIKE SYNOVIAL CELL; SYNOVITIS; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR-B1; BIOMARKER;

机译：类风湿关节炎;成纤维样滑膜细胞;滑膜炎;血栓素1;转化生长因子-B1;生物标志物;

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1. Upregulation of Thrombospondin 1 Expression in Synovial Tissues and Plasma of Rheumatoid Arthritis: Role of Transforming Growth Factor-beta 1 toward Fibroblast-like Synovial Cells (vol 42, pg 943, 2015) [J] . Suzuki T., Iwamoto N., Yamasaki S., The Journal of rheumatology . 2017,第1期

机译：血压出素1表达在类风湿性关节炎的滑膜组织和血浆中的上调：将生长因子-β1转化为成纤维细胞样滑膜细胞的作用（Vol 42，PG 943,2015）
2. Heat shock protein 70 membrane expression on fibroblast-like synovial cells derived from synovial tissue of patients with rheumatoid and juvenile idiopathic arthritis. [J] . Nguyen TT, Gehrmann M, Zlacka D, Scandinavian journal of rheumatology . 2006,第6期

机译：类风湿和幼年特发性关节炎患者滑膜组织中成纤维样滑膜细胞上热休克蛋白70膜的表达。
3. Stimulatory Role of Lysophosphatidic Acid in Cyclooxygenase-2 Induction by Synovial Fluid of Patients with Rheumatoid Arthritis in Fibroblast-Like Synovial Cells [J] . Hiromi Nochi, Hideaki Tomura, Masayuki Tobo, The journal of immunology . 2008,第7期

机译：溶血磷脂酸对类风湿关节炎患者成纤维细胞样滑膜细胞滑液诱导环氧合酶-2的刺激作用
4. Immunogenic HLA-DR-presented-peptides Identified from Clinical Samples of Synovial Tissue/Fluid and Peripheral Blood from Patients with Rheumatoid Arthritis or Lyme Arthritis [C] . Qi Wang, Elise E. Drouin, Chunxiang Yao, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：免疫原性HLA-DR呈递肽，从类风湿性关节炎或莱姆关节炎患者的滑膜组织/液体和外周血的临床样本中鉴定出来
5. An increase in the frequency of hprt mutant T lymphocytes in the peripheral blood, synovial fluid, and synovial tissue of rheumatoid arthritis patients. [D] . Cannons, Jennifer. 1997

机译：类风湿性关节炎患者外周血，滑液和滑膜组织中hprt突变T淋巴细胞的频率增加。
6. Detection of transforming growth factor-beta in rheumatoid arthritis synovial tissue: lack of effect on spontaneous cytokine production in joint cell cultures. [O] . F M Brennan, D Chantry, M Turner, 1990

机译：类风湿关节炎滑膜组织中转化生长因子-β的检测：对关节细胞培养中自发细胞因子产生的影响不足。
7. Expression of interferon-gamma (IFN-δ), IL-10, IL-12 and transforming growth factor-beta (TGF-β) mRNA in synovial fluid cells from patients in the early and late phases of rheumatoid arthritis (RA) [O] . BUCHT, A., LARSSON, P., WEISBROT, L., 2007

机译：类风湿关节炎（RA）患者滑液细胞中干扰素-γ（IFN-δ），IL-10，IL-12和转化生长因子-β（TGF-β）mRNA的表达
8. Differential Reactivity of Rheumatoid Synovial Cells and Serum Rheumatoid Factors to Human Immunoglobulin G Subclasses 1 and 3 and Their CH3 Domains in Rheumatoid Arthritis [R] . Robbins, D. L., Benisek, W. F., Benjamini, E., 1987

机译：类风湿关节炎细胞和血清类风湿因子对人免疫球蛋白G亚类1和3及其类风湿性关节炎CH3区的差异反应性

Upregulation of Thrombospondin 1 Expression in Synovial Tissues and Plasma of Rheumatoid Arthritis: Role of Transforming Growth Factor-beta 1 toward Fibroblast-like Synovial Cells

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