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首页> 外文期刊>The Journal of Thoracic and Cardiovascular Surgery >Modification of surgical technique for ascending aortic atherosclerosis: Impact on stroke reduction in coronary artery bypass grafting.
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Modification of surgical technique for ascending aortic atherosclerosis: Impact on stroke reduction in coronary artery bypass grafting.

机译:升主动脉粥样硬化手术技术的改进:对减少冠状动脉搭桥术中风的影响。

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OBJECTIVE: Use of epiaortic scanning in coronary surgery is still a matter of debate. It is unclear whether the findings obtained by epiaortic scanning lead to effective changes in surgical technique that may reduce stroke rates. METHODS: Epiaortic scanning was performed in 352 patients undergoing primary coronary artery bypass grafting before opening the pericardium using a 7.5-MHz ultrasonic probe. In the presence of moderate atherosclerosis (maximum aortic wall thickness of 3 to 5 mm), primarily single aortic crossclamping was carried out. In cases of severe sclerosis (maximum aortic wall thickness > 5 mm), aortic no-touch techniques on the beating heart were used. RESULTS: The degree of ascending aortic atherosclerosis was normal or mild in 151 patients (42.9%), moderate in 167 patients (47.5%), and severe in 34 patients (9.6%). The operative technique was modified in 31.1% of patients with moderate aortic sclerosis and in 91.2% of patients with severe aortic sclerosis. Perioperative mortality was 0.0% for mild disease, 3.0% for moderate disease, and 8.8% for severe disease (P =.005). Corresponding stroke rates reached 2.0%, 2.4%, and 2.9% (P =.935). Logistic regression adjusting for EuroSCORE showed that ascending aortic atherosclerosis was an independent predictor of perioperative mortality (P =.013, odds ratio 1.67, confidence interval 1.11-2.50). The influence of aortic disease on the stroke prevalence was probably due to chance (P =.935), demonstrating a potentially positive effect of operative modifications concerning stroke caused by aortic manipulation. CONCLUSIONS: We conclude that intraoperative screening of coronary artery bypass grafting patients by epiaortic scanning can reveal useful information about the operative risk and with an aortic no-touch concept, perioperative stroke rates in high-risk patients may be lower than predicted.
机译:目的:在冠状动脉外科手术中使用表皮主动脉扫描仍存在争议。尚不清楚通过epi动脉扫描获得的发现是否会导致手术技术的有效改变,从而降低卒中发生率。方法:对352例行原发性冠状动脉搭桥术的患者进行了主动脉扫描,然后使用7.5MHz超声探头打开心包。在中度动脉粥样硬化(主动脉壁最大厚度为3至5 mm)的情况下,主要进行单主动脉交叉钳夹术。对于严重的硬化症(最大主动脉壁厚度> 5 mm),在跳动的心脏上使用主动脉无接触技术。结果:升主动脉粥样硬化程度在151例(42.9%)是正常或轻度,在167例(47.5%)是中度,在34例(9.6%)是严重。 31.1%的中度主动脉硬化患者和91.2%的重度主动脉硬化患者对手术技术进行了修改。轻度疾病的围手术期死亡率为0.0%,中度疾病为3.0%,重度疾病为8.8%(P = .005)。相应的卒中发生率分别达到2.0%,2.4%和2.9%(P = .935)。对EuroSCORE进行的Logistic回归调整显示,升主动脉粥样硬化是围手术期死亡率的独立预测因子(P = .013,优势比1.67,置信区间1.11-2.50)。主动脉疾病对中风患病率的影响可能是由于偶然因素造成的(P = .935),这表明因主动脉操作引起的中风的手术改良有潜在的积极作用。结论:我们得出的结论是,通过表皮主动脉扫描对冠状动脉搭桥术患者进行术中筛查可以揭示有关手术风险的有用信息,并且采用主动脉无接触概念,高危患者的围手术期卒中发生率可能低于预期。

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