Editorial Comment: The recently published report by Li et al. has received considerable attention from the press and from the National Institute of Environmental and Health Science because it is the first evidence on noxious effects of bisphenol A (BPA) on human male reproductive function, arid one of the very few studies that may support the need to examine the occupational risks for workers in the manufacture and processing of this chemical. This interesting paper was reviewed in the accompanying editorial commentary in the same journal (RM Sharpe, Hum Reprod 2010;25:292-4). BPA is one of the top selling chemical products in the world, as the monomer to manufacture polycarbonate plastic (most food and beverage cans), epoxi resins, dental sealants, and other plastics, and is released to water and the ecosystem, so that both environmental and occupational exposure are of utmost importance for health regulatory and research agencies all over the world.
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