首页> 外文期刊>The Journal of Urology >Bilateral caudal epidural neuromodulation for refractory urinary retention: a salvage procedure.
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Bilateral caudal epidural neuromodulation for refractory urinary retention: a salvage procedure.

机译:难治性尿retention留的双侧尾硬膜外神经调节:抢救程序。

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PURPOSE: Sacral neuromodulation with InterStim is approved for idiopathic urinary retention with a success rate of approximately 69%. To our knowledge currently no alternatives exist for patients in whom S3 neuromodulation fails. We report a new technique and our experience with bilateral caudal epidural neuromodulation in patients in urinary retention in whom unilateral or bilateral S3 InterStim failed. MATERIALS AND METHODS: Eight patients with multifactorial urinary retention in whom S3 InterStim previously failed underwent retrograde placement of bilateral tined leads into the caudal epidural space for sacral nerve stimulation. Patients with a 50% or greater clinical response underwent stage 2 Synergy-Versitrel implantable pulse generator placement. Patients were evaluated with voiding diaries, the Urinary Distress Inventory Questionnaire short form, quality of life assessment, need for catheterization and post-void residual urine preoperatively, and 6 months after implantation. RESULTS: Five of the 8 patients experienced return of micturition and underwent placement of a permanent implantable pulse generator. At 6-month followup 4 of the 5 patients voided to completion. One patient improved more than 50% and now catheterizes once daily with a post-void residual urine of 200 cc. There was a significant decrease in obstructive symptoms on the Urinary Distress Inventory Questionnaire short form and improved overall quality of life. CONCLUSIONS: To our knowledge this is the first report of the use of bilateral caudal epidural neuromodulation for refractory urinary retention. This therapy can be successful in patients in whom prior InterStim therapy failed.
机译:目的:使用InterStim进行S神经调节已被批准用于特发性尿retention留,成功率约为69%。据我们所知,目前尚无其他替代方法可用于S3神经调节失败的患者。我们报告了一种新技术和我们的经验,对单侧或双侧S3 InterStim失败的尿retention留患者进行双侧尾硬膜外神经调节。材料与方法:8例S3 InterStim先前失败的多因素尿retention留患者接受了双侧锡膏逆行放置至c硬膜外腔,以神经刺激。具有50%或更高临床反应的患者接受2期Synergy-Versitrel植入式脉冲发生器植入。对患者进行了排尿日记,尿毒情况调查问卷的简短形式,生活质量评估,术前和植入后6个月是否需要导尿和排尿后是否残留尿液。结果:8位患者中有5位经历了排尿恢复,并放置了永久性植入式脉冲发生器。在6个月的随访中,5例患者中有4例无效。一名患者的病情改善了50%以上,现在每天进行一次导管插入,术后排空后残留尿量为200 cc。尿痛库存调查问卷简短形式的阻塞性症状明显减少,并且改善了整体生活质量。结论:据我们所知,这是首次使用双侧尾硬膜外神经调节治疗难治性尿retention留。在先前的InterStim治疗失败的患者中,这种治疗可能会成功。

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