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USE OF URINARY NGAL TO DIAGNOSE UNILATERAL AND BILATERAL URINARY OBSTRUCTION

机译:使用尿NGAL诊断单侧和双侧尿路阻塞

摘要

In one embodiment, the present invention is directed to methods for diagnosis of urinary tract obstruction (UTO), and to methods for distinguishing between unilateral and bilateral UTO. In some aspects, the diagnostic methods of the invention are based on determining whether a bodily fluid sample, such as a urine sample, contains an amount of NGAL protein that exceeds or is less than a certain threshold level, or that falls within a certain range. The present invention also provides diagnostic kits for the diagnosis of UTO and for distinguishing between unilateral and bilateral UTO.
机译:在一个实施例中,本发明涉及用于诊断尿路阻塞(UTO)的方法,并且涉及用于区分单侧和双侧UTO的方法。在一些方面,本发明的诊断方法是基于确定体液样品(例如尿液样品)是否含有一定量的NGAL蛋白,该数量的NGAL蛋白大于或小于某个阈值水平,或者是否落入某个范围内。本发明还提供了用于诊断UTO并区分单侧和双侧UTO的诊断试剂盒。

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