首页> 外文期刊>The Journal of Urology >The actual incidence of bladder perforation following transurethral bladder surgery.
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The actual incidence of bladder perforation following transurethral bladder surgery.

机译:经尿道膀胱手术后膀胱穿孔的实际发生率。

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PURPOSE: In this prospective study we evaluated the incidence of bladder perforation after transurethral bladder tumor resection. MATERIALS AND METHODS: A total of 36 patients (33 male, 3 female, mean age +/- SD 65.6 +/- 11.43 [range 26 to 81]) with a solid mass in the bladder (mean 20.3 +/- 8.7 mm, range 5 to 40) were included in the study. Transurethral resections were performed with a 24Fr resectoscope. After the procedure an 18Fr Foley catheter was inserted into the bladder and 400 ml of 1/4 saline diluted contrast solution was instilled under gravity from 60 cm above the bladder. Complete filling and post-drainage radiographs were taken and examined for any evidence of extravasation. Regular evaluations with cystoscopy and ultrasound/computerized tomography were done to detect possible tumor recurrence and perivesical seeding. RESULTS: Histopathological examination of the tumors showed transitional cell carcinoma in 35 patients and chronic eosinophilic cystitis in 1. Review of the cystograms revealed various degrees of extraperitoneal contrast extravasation around the resected area in 21 patients (58.3%). The only statistically significant difference between patients with and without extravasation was in tumor size (logistic stepwise regression p = 0.030,) among factors tested including patient age and localization, number of foci, tumor grade and stage. No apparent clinical problems requiring medical or surgical intervention other than urethral catheterization developed and no evidence of extravesical tumor seeding as per ultrasound and/or computerized tomography was seen during a mean followup of 21.9 months (range 7 to 40). CONCLUSIONS: The extravasation of urine (asymptomatic perforation) after transurethral bladder tumor resection may occur much more frequently than believed or reported. It seems that this extravasation does not impose a significant risk of extravesical tumor seeding.
机译:目的:在这项前瞻性研究中,我们评估了经尿道膀胱肿瘤切除术后膀胱穿孔的发生率。材料与方法:共有36名患者(膀胱平均质量为20.3 +/- 8.7毫米,男2例,女3例,平均年龄+/- SD 65.6 +/- 11.43 [范围26至81])。研究范围包括5到40)。经24Fr电切镜行经尿道切除术。手术后,将18Fr Foley导管插入膀胱,并在重力作用下从膀胱上方60 cm滴入400 ml 1/4盐水稀释的造影剂。拍摄了完整的填充和引流后的X光片,并检查了是否有渗出的迹象。定期进行膀胱镜检查和超声/计算机断层扫描评估,以发现可能的肿瘤复发和根治性播种。结果:肿瘤的组织病理学检查显示35例患有移行细胞癌,1例患有慢性嗜酸性粒细胞性膀胱炎。复查膀胱造影显示21例患者的切除区域周围有不同程度的腹膜外造影剂渗出。(58.3%)。在有和没有外渗的患者之间唯一的统计上显着差异是所测试的因素之间的肿瘤大小(逻辑逐步回归p = 0.030),包括患者年龄和位置,病灶数量,肿瘤等级和分期。在平均21.9个月的随访中(7至40个月),没有发现需要除尿道导管插入术以外需要医学或外科手术干预的明显临床问题,也没有发现根据超声和/或计算机断层摄影术发现膀胱外肿瘤播种的证据。结论:经尿道膀胱肿瘤切除术后尿液外溢(无症状穿孔)的发生频率可能​​比人们认为的或报道的要高得多。看来,这种外渗不会给膀胱外肿瘤的植入带来很大的风险。

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