Bromodecarboxylation of Quinoline Salicylic Acids:Increasing the Diversity of Accessible Substituted Quinolines

摘要

Quinoline salicylic acids underwent bromodecarboxylationat room temperature upon treatment with N-bromosucci-nimide. A wide variety of functional groups was tolerated.Several one-pot transformations were also carried out,allowing the preparation of diverse 4-substituted quinolines.