Iodine-induced regioselective C-C and C-N bonds formation of N -protected indoles

摘要

A mild, metal-free, and environmently benign iodine-promoted regioselective C-C and C-N bonds formation of N-protected indole derivatives giving 2,3′-biindoles 2 and 4-(1H-indol-2-yl)morpholines 4 is successfully demonstrated. Various bioactive 2,3′-biindoles and 4-(1H-indol-2-yl) morpholines, bearing electron-rich to moderately electron-poor substituents, can be prepared in moderate to good yields.