首页> 外文期刊>The journal of pain: official journal of the American Pain Society >Does opiate use in traumatically injured individuals worsen pain and psychological outcomes?
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Does opiate use in traumatically injured individuals worsen pain and psychological outcomes?

机译:在遭受创伤的个人中使用鸦片制剂会加剧疼痛和心理后果吗?

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Opiate use for chronic pain is becoming increasingly controversial. There has been a shift away from supporting the use of opiates for treatment of chronic pain. In addition to lack of effectiveness, concerns for adverse clinical outcomes, addiction, and death have provided the impetus for this change. The purpose of this study was to investigate the percent of trauma patients still using opiates, their pain levels, and psychological outcomes 4 months posttrauma. This was a study to evaluate chronic pain at 4 months posttrauma in 101 participants from a single level 1 trauma center. Eighty of the 101 participants developed chronic pain 4 months after their initial traumatic injury (79%). Of those who developed chronic pain, 27 (26%) were still using opiates. Those using narcotics at 4 months posttrauma had significantly more pain, life interference, depression, and anxiety. Posttraumatic stress disorder (PTSD) was not significantly influenced by narcotic use in this analysis. However, the mean associated with those using narcotics was higher and diagnostic for PTSD. Those taking opiates did not have significantly better relief from their pain using treatments or medications than those not using opiates (F = 8, P = .08). These findings bring into question the appropriate use of opiates for chronic pain and the possible exacerbating effects on pain and psychopathology in traumatically injured patients.This article identifies data that provide evidence that narcotic pain medication needs to be used carefully in traumatically injured patients with chronic pain, especially in those individuals with comorbid psychological pathology.
机译:阿片类药物用于慢性疼痛的争议越来越大。从支持使用阿片类药物治疗慢性疼痛已经发生了转变。除了缺乏有效性外,对不良临床结果,成瘾性和死亡的担忧也为这一变化提供了动力。这项研究的目的是调查创伤后4个月仍使用鸦片制剂的创伤患者的百分比,他们的疼痛程度以及心理结果。这项研究评估了来自单个1级创伤中心的101名参与者在创伤后4个月的慢性疼痛。 101名参与者中有80名在其最初的外伤后4个月出现了慢性疼痛(79%)。在那些患有慢性疼痛的人中,有27人(占26%)仍在使用鸦片制剂。创伤后4个月使用麻醉药的人疼痛,生活干扰,抑郁和焦虑明显增加。在此分析中,麻醉后使用对创伤后应激障碍(PTSD)的影响不明显。但是,与使用麻醉品的人相关的平均值较高,并且对PTSD具有诊断意义。那些服用鸦片制剂的人与没有使用鸦片制剂的人相比,使用治疗或药物缓解疼痛的效果没有明显改善(F = 8,P = .08)。这些发现使人们对鸦片类药物在慢性疼痛中的适当使用以及可能对加重创伤患者的疼痛和心理病理学的恶化产生质疑。本文确定了提供证据的证据,表明在长期受创伤的创伤患者中需要谨慎使用麻醉性止痛药,尤其是那些患有心理疾病的患者。

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