Application of Grey Relational Analysis to Hypertension Clinical Trials

摘要

It has become very important to choose the appropriate clinical trial method. In current randomized clinical trials of hypertension, however, there are some flaws including ethical issues, long time, huge expenses, excessive confounding factors and difficult quality control. The application of grey relational analysis (e.g., its evaluation model and comparison model) hypertension clinical trials allows evaluation or comparison without placebo control, and allows accurate results from small-sized samples. Being used at the level of multivariation or in overall benefit evaluation, grey relational analysis can also assess the individualized treatment effect on hypertension. Mutual result exactness is promising in the combined application of grey relational analysis with other methods of hypertension clinical trials.