Acute psychosis associated with anti-NMDA-receptor antibodies and bilateral ovarian teratomas: a case report.

摘要

To the Editor: Paraneoplastic limbic encephalopathy, initially described in 1968, is a rare disorder associated with neoplasms and characterized by symptoms and signs of limbic system disorder. A subtype of limbic encephalopathy with autoantibodies to the NR1 subunit of the N-methyl-D-aspartate (NMDA) receptor has been described by Dalmau et al.Of 100 patients, 77 presented first to a psychiatrist with anxiety, agitation, bizarre behavior, or psychotic symptoms. The other 23 first presented with a seizure or memory impairment.