Background: Divided nevus of eyelid is a rare form of congenital nevus. It can cause cosmetic and psychological problems. The aim of the treatment is to reliably remove the lesion with minimal functional impairment, to improve the cosmetics, and to prevent canceration. Methods: The paired nevi were treated with CO2 laser by local anesthesia. Ablation was stopped after all the visible pigment tissues were removed and normal tissues became visible, shaping the basilar part to get good cosmetic results, avoiding thermally damaging the lower dermis as far as possible to minimize the side effect. Results: It showed good cosmetic results 5 months after the last operation without any functional impairment except for a little repigment on the upper lid, superficial scar on the lower lid, and hypopigmentation on both of the wounds. Conclusions: With the advantages of simplicity, precision, and effectiveness, CO2 laser can be recommended to treat small divided nevus with special type and clinical characteristics. It can help to simplify the treatment, get good cosmetic results, and avoid skin graft.
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