'Paradoxical' Low-Flow, Low-Gradient Severe Aortic Valve Stenosis: An Entity with Limited Improvement Following Transcatheter Aortic Valve Implantation

摘要

Background and aim of the study: The aim of this single-center observational study was to determine the outcome of patients with 'paradoxical' low-flow, low-gradient aortic valve stenosis (PLF-LG-AS) after transcatheter aortic valve implantation (TAVI). Methods: Based on pre-procedural echocardiographic data, a total of 150 patients with severe aortic valve stenosis (AS) (indexed aortic valve area (AVA) < 0.6 cm2/m2) who underwent TAVI at the authors' institution were allocated retrospectively to three groups: Group 1: PLF-LG-AS (ejection fraction (EF) >50%, indexed stroke volume (SV) <35 ml/m2, mean AV gradient <40 mmHg; n = 30); Group 2: Classical low-flow, low-gradient AS (CLF-LG-AS: EF <50%, SV <35 ml/m2, mean AV gradient <40 mmHg; n = 21); and Group 3: High-gradient AS (HG-AS: EF < or > 50%, mean AV gradient >40 mmHg; n = 99).