Analysis of the quinolone-resistance determining region of the gyrA gene and the analogous region of the parC gene in Ureaplasma parvum and Ureaplasma urealyticum detected in first-void urine of men with non-gonococcal urethritis

摘要

Many reports have suggested that Ureaplasma parvum and/or Ureaplasma urealyticum may be associated with urogenital infections, infertility, and adverse pregnancy outcomes. However, their pathogenic roles have remained somewhat controversial. As for the management of the ureaplasma infections, there have been only a limited number of reports on surveillance for antimicrobial resistance in ureaplasma clinical strains, which is crucial for providing therapy empirically.