SYNTHESIS AND STEREOCHEMICAL STRUCTURE OF DERIVATIVES OF 2-SUBSTITUTED3-CYCLOHEXENYLAMIDOQUINAZOLIN-4-ONES OBTAINED FROM N '-CYCLOHEXENECARBONYL-SUBSTITUTED HYDRAZIDES OF 2-AMINOBENZOIC ACID AND CERTAIN ORTHOESTERS

摘要

In the reaction of N'-cyclohexenecarbonyl-substituted hydrazides of 2-aminobenzoic acid with the trialkyl esters of formic, acetic, valeric, and benzoic acids at room temperature 3-cyclohexenylamidoquinazolin-4-ones with the respective substituent at the C-2 atom of the quinazoline ring were obtained. The spatial structure of the obtained compounds was studied by homonuclear and heteronuclear NMR.