4-HYDROXY-2-QUINOLONES. 201. SYNTHESIS, STRUCTURE, AND DIURETIC ACTIVITY OF HYDROXY- AND ALKOXY-ANILIDES OF 6-HYDROXY-2-METHYL-4-OXO-2,4-DIHYDRO-1H-PYRROLO[3,2,1-ij]QUINOLINE-5-CARBOXYLIC ACID

I. V. Ukrainets; N. Yu. Golik; A. L. Shemchuk; V. N. Kravchenko

首页> 外文期刊>Chemistry of heterocyclic compounds >4-HYDROXY-2-QUINOLONES. 201. SYNTHESIS, STRUCTURE, AND DIURETIC ACTIVITY OF HYDROXY- AND ALKOXY-ANILIDES OF 6-HYDROXY-2-METHYL-4-OXO-2,4-DIHYDRO-1H-PYRROLO[3,2,1-ij]QUINOLINE-5-CARBOXYLIC ACID

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4-HYDROXY-2-QUINOLONES. 201. SYNTHESIS, STRUCTURE, AND DIURETIC ACTIVITY OF HYDROXY- AND ALKOXY-ANILIDES OF 6-HYDROXY-2-METHYL-4-OXO-2,4-DIHYDRO-1H-PYRROLO[3,2,1-ij]QUINOLINE-5-CARBOXYLIC ACID

机译：4-羟基-2-喹诺酮201. 6－羟基－2－甲基－4－OXO－2，4－二羟基－1H－吡咯并[3,2,1-ij] QUINOLINE-5的羟基和烷基苯的合成，结构和利尿活性-羧酸

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Hydroxy- and alkoxyanilides of 6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acids have been synthesized as potential diuretic agents. Features of their purification, their steric structure, and biological activity are discussed.

机译：已经合成了6-羟基-2-甲基-4-氧代-2,4-二氢-1H-吡咯并[3,2,1-ij]喹啉-5-羧酸的羟基和烷氧基苯胺作为潜在的利尿剂。讨论了其纯化，空间结构和生物学活性的特征。

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《Chemistry of heterocyclic compounds》 |2011年第9期|共6页
作者
I. V. Ukrainets; N. Yu. Golik; A. L. Shemchuk; V. N. Kravchenko;
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原文格式 PDF
正文语种 eng
中图分类杂环化合物;
关键词
anilides; 4-hydroxy-2-oxoquinoline-3-carboxylic acids; amidation; diuretic activity; X-ray structural analysis;

机译：苯甲酸酯;4-羟基-2-氧代喹啉-3-羧酸;酰胺化;利尿活性;X射线结构分析;

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1. 4-HYDROXY-2-QUINOLONES. 201. SYNTHESIS, STRUCTURE, AND DIURETIC ACTIVITY OF HYDROXY- AND ALKOXY-ANILIDES OF 6-HYDROXY-2-METHYL-4-OXO-2,4-DIHYDRO-1H-PYRROLO[3,2,1-ij]QUINOLINE-5-CARBOXYLIC ACID [J] . I. V. Ukrainets, N. Yu. Golik, A. L. Shemchuk, Chemistry of heterocyclic compounds . 2011,第9期

机译：4-羟基-2-喹诺酮201. 6－羟基－2－甲基－4－OXO－2，4－二羟基－1H－吡咯并[3,2,1-ij] QUINOLINE-5的羟基和烷基苯的合成，结构和利尿活性-羧酸
2. 4-HYDROXY-2-QUINOLONES. 233*. SYNTHESIS AND DIURETIC ACTIVITY OF 9-BROMO-7-HYDROXY-5-OXO-2,3-DIHYDRO-1H,5H-PYRIDO[3,2,1-ij]QUINOLINE-6-CARBOXYLIC ACID ANILIDES [J] . I.V. Ukrainets, N. Yu. Golik, I. N. Chernenok Chemistry of heterocyclic compounds . 2013,第9期

机译：4-羟基-2-喹诺酮233 *。 9-BROMO-7-HYDROXY-5-OXO-2,3-DIHYDRO-1H，5H-PYRIDO [3,2,1-ij] QUINOLINE-6-羧酸苯胺的合成及利尿活性
3. The Study of the Structure—Diuretic Activity Relationship in a Series of New N-(Arylalkyl)-6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo-[3,2,1-ij]quinoline-5-carboxamides [J] . Igor V. Ukrainets, Mykola Y. Golik, Lyudmila V. Sidorenko, Scientia pharmaceutica . 2018,第3期

机译：一系列新的N-（芳烷基）-6-羟基-2-甲基-2-氧-4-甲基-2,4-二氢-1H-吡咯-[3,2,1-ij的结构-利尿活性关系的研究]喹啉-5-羧酰胺
4. Effect of Acidity and Structures of Supported Tungstophosphoric Acid on its Catalytic Activity and Selectivity in Liquid Phase Synthesis of Ethylbenzene [C] . Yongqiang Zhang, Zexue Du, Enze Min Asia-Pacific Congress on Catalysis . 2003

机译：支撑钨磷酸酸度与结构对乙苯液相合成催化活性及选择性的影响
5. The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z8Z11Z13E)-eicosatetraenoic acid: structure-activity relationship and mechanism of action. [O] . K Petrich, P Ludwig, H Kühn, 1996

机译：15-脂氧合酶产物（15S）-羟基-（5Z8Z11Z13E）-二十碳四烯酸对人多形核白细胞中花生四烯酸5-脂氧合的抑制作用：结构-活性关系和作用机理。
6. Synthesis and diuretic properties of n-aryl- 6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1h-pyrrolo 3,2,1-ijquinoline-5-carboxamides with electron-acceptor substituents in the anilide fragment [O] . I. V. Ukrainets, M. Yu. Golik, O. L. Shemchuk, 2013

机译：N-芳基-6-羟基-2-甲基-4-氧代-2,4-二氢-1H-吡咯的合成和利尿性能3,2,1-IJ喹啉-5-甲酰胺，具有电子受体取代基苯胺片段

4-HYDROXY-2-QUINOLONES. 201. SYNTHESIS, STRUCTURE, AND DIURETIC ACTIVITY OF HYDROXY- AND ALKOXY-ANILIDES OF 6-HYDROXY-2-METHYL-4-OXO-2,4-DIHYDRO-1H-PYRROLO[3,2,1-ij]QUINOLINE-5-CARBOXYLIC ACID

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