SYNTHESIS OF HETEROCYCLES ON THE BASIS OF ARYLATION PRODUCTS OF UNSATURATED COMPOUNDS. 19.* ARYLATION OF 2-ACETYLTHIOPHENE AND THE SYNTHESIS OF 2-(5-ARYL-2-THIENYL)-4-QUINOLINECARBOXYLIC ACIDS

摘要

The reaction of 2-acetylthiophene with acetylthiophene with arenediazonium chlorides in the presence of cupric chloride as catalyst gives 2-acetyl-5-arylthiophenes. These products react with 5-chloro- and 5-bromoisatins to give 6-chloro- and 6-bromo-substituted 2-(5-aryl-2-thienyl)-4-quinolinecarboxylic acids.