Efficient and Rapid One-pot Conversions of Aldehydes into Nitriles and Ketones into Amides Using SIlica Chloride under Microwave Irradiation

摘要

Under solvent free conditions,several aldehydes and ketones were efficiently and rapidly converted into the corre-sponding nitriles and amides respectively by treatment with hydroxylamine hydrochloride under microwave irradiation using silica chloride as catalyst.The yields of the products were very high and the time required for their preparation was very short compared to conventional heating experiments.