Food protein-induced enterocolitis syndrome by cow's milk proteins passed through breast milk.

摘要

Food protein-induced enterocolitis syndrome (FPIES) is an uncommon non-IgE-mediated gastrointestinal food hypersensi-tivity of infancy with an incidence reportedly increasing. Symptoms include profuse vomiting and diarrhea arising within 1 to 3 hours after ingestion of the causative food and may lead to dehydration, hypotension, and shock. Hypothermia, pallor, and lethargy are other common features; laboratory tests usually show neutrophilia, thrombocytosis, and metabolic acidosis.1 Cow's milk and soy-based formulas are the most frequently involved foods, but FPIES caused by solid foods has also been described.1"4 Breast-feeding is considered a protective factor, and to our knowledge, there have been no reports of FPIES in breast-fed infants.2'3 We describe the first case of a young infant with FPIES caused by cow's milk proteins (CMPs) passed through the breast milk after accidental maternal ingestion.