Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos

Pino-Yanes Maria; Gignoux Christopher R.; Galanter Joshua M.; Levin Albert M.; Campbell Catarina D.; Eng Celeste; Huntsman Scott; Nishimura Katherine K.; Gourraud Pierre-Antoine; Mohajeri Kiana; ORoak Brian J.; Hu Donglei; Mathias Rasika A.; Nguyen Elizabeth A.; Roth Lindsey A.; Padhukasahasram Badri; Moreno-Estrada Andres; Sandoval Karla; Winkler Cheryl A.; Lurmann Fred; Davis Adam; Farber Harold J.; Meade Kelley; Avila Pedro C.; Serebrisky Denise; Chapela Rocio; Ford Jean G.; Lenoir Michael A.; Thyne Shannon M.; Brigino-Buenaventura Emerita; Borrell Luisa N.; Rodriguez-Cintron William; Sen Saunak; Kumar Rajesh; Rodriguez-Santana Jose R.; Bustamante Carlos D.; Martinez Fernando D.; Raby Benjamin A.; Weiss Scott T.; Nicolae Dan L.; Ober Carole; Meyers Deborah A.; Bleecker Eugene R.; Mack Steven J.; Hernandez Ryan D.; Eichler Evan E.; Barnes Kathleen C.; Williams L. Keoki; Torgerson Dara G.; Burchard Esteban G.

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Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos

机译：全基因组关联研究和混合物映射揭示了与拉丁美洲人总IgE水平相关的新基因座

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Background: IgE is a key mediator of allergic inflammation, and its levels are frequently increased in patients with allergic disorders.

机译：背景：IgE是过敏性炎症的关键介质，在过敏性疾病患者中其水平经常升高。

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来源
《The Journal of Allergy and Clinical Immunology》 |2015年第6期|共9页
作者
Pino-Yanes Maria; Gignoux Christopher R.; Galanter Joshua M.; Levin Albert M.; Campbell Catarina D.; Eng Celeste; Huntsman Scott; Nishimura Katherine K.; Gourraud Pierre-Antoine; Mohajeri Kiana; ORoak Brian J.; Hu Donglei; Mathias Rasika A.; Nguyen Elizabeth A.; Roth Lindsey A.; Padhukasahasram Badri; Moreno-Estrada Andres; Sandoval Karla; Winkler Cheryl A.; Lurmann Fred; Davis Adam; Farber Harold J.; Meade Kelley; Avila Pedro C.; Serebrisky Denise; Chapela Rocio; Ford Jean G.; Lenoir Michael A.; Thyne Shannon M.; Brigino-Buenaventura Emerita; Borrell Luisa N.; Rodriguez-Cintron William; Sen Saunak; Kumar Rajesh; Rodriguez-Santana Jose R.; Bustamante Carlos D.; Martinez Fernando D.; Raby Benjamin A.; Weiss Scott T.; Nicolae Dan L.; Ober Carole; Meyers Deborah A.; Bleecker Eugene R.; Mack Steven J.; Hernandez Ryan D.; Eichler Evan E.; Barnes Kathleen C.; Williams L. Keoki; Torgerson Dara G.; Burchard Esteban G.;
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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
IgE; genome-wide association study; admixture mapping; allergy; asthma; next-generation sequencing; Latinos; Hispanics; minority populations;

机译：IgE;全基因组关联研究;混合物作图;变态反应;哮喘;下一代测序;拉丁裔;西班牙裔;少数民族;

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1. Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos [J] . Pino-Yanes Maria, Gignoux Christopher R., Galanter Joshua M., The Journal of Allergy and Clinical Immunology . 2015,第6期

机译：全基因组关联研究和混合物映射揭示了与拉丁美洲人总IgE水平相关的新基因座
2. Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture [J] . Alarcon-Riquelme Marta E., Ziegler Julie T., Molineros Julio, Arthritis & rheumatology. . 2016,第4期

机译：在美洲祖先人口中的全基因组关联研究揭示了新型系统性红斑狼疮风险基因座和欧洲混合物的作用
3. Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci [J] . Manousaki Despoina, Mitchell Ruth, Dudding Tom, The American Journal of Human Genetics . 2020,第3期

机译：基因组 - 维生素D级别的协会研究揭示了69个独立基因座
4. GENOME-WIDE INTERACTION WITH SELECTED TYPE 2 DIABETES LOCI REVEALS NOVEL LOCI FOR TYPE 2 DIABETES IN AFRICAN AMERICANS [C] . JACOB M. KEATON, JACKLYN N. HELLWEGE, MAGGIE C. Y. NG, Pacific Symposium on Biocomputing . 2017

机译：与选定的2型糖尿病座的基因组相互作用揭示了非洲裔美国人2型糖尿病的新型基因座
5. Measuring and using genetic ancestry information in genome-wide admixture mapping and association mapping of complex diseases. [D] . Tian, Chao. 2009

机译：在复杂疾病的全基因组混合物映射和关联映射中测量和使用遗传祖先信息。
6. Genome-wide Association Study and Admixture Mapping Reveal New Loci Associated with Total IgE Levels in Latinos [O] . Maria Pino-Yanes, Christopher R. Gignoux, Joshua M. Galanter, -1

机译：全基因组关联研究和混合物映射揭示了与拉丁美洲人总IgE水平相关的新基因座
7. Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits. [O] . Tamar Sofer, Leslie J Baier, Sharon R Browning, 2017

机译：拉丁美洲西班牙裔社区健康研究/研究中的混合物映射揭示了与血压特征相关的遗传关联区域。

Genome-wide association study and admixture mapping reveal new loci associated with total IgE levels in Latinos

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