Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment

Turner Steve; Francis Ben; Vijverberg Susanne; Pino-Yanes Maria; Maitland-van der Zee Anke H.; Basu Kaninika; Bignell Lauren; Mukhopadhyay Somnath; Tavendale Roger; Palmer Colin; Hawcutt Daniel; Pirmohamed Munir; Burchard Esteban G.; Lipworth Brian

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Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment

机译：儿童哮喘急性发作和Arg16 beta（2）-受体多态性：按治疗分层的荟萃分析

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Background: The Gly-to-Arg substitution at the 16 position (rs1042713) in the beta(2)-adrenoceptor gene (ADRB2) is associated with enhanced downregulation and uncoupling of beta(2)-receptors.

机译：背景：β（2）-肾上腺素受体基因（ADRB2）中16位（rs1042713）的Gly-Arg取代与增强的beta（2）-受体下调和解偶联相关。

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来源
《The Journal of Allergy and Clinical Immunology》 |2016年第1期|共12页
作者
Turner Steve; Francis Ben; Vijverberg Susanne; Pino-Yanes Maria; Maitland-van der Zee Anke H.; Basu Kaninika; Bignell Lauren; Mukhopadhyay Somnath; Tavendale Roger; Palmer Colin; Hawcutt Daniel; Pirmohamed Munir; Burchard Esteban G.; Lipworth Brian;
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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Adrenergic receptors; asthma; child; disease exacerbation; therapeutics;

机译：肾上腺素能受体;哮喘;儿童;疾病加重;治疗药物;

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1. Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment [J] . Turner Steve, Francis Ben, Vijverberg Susanne, The Journal of Allergy and Clinical Immunology . 2016,第1期

机译：儿童哮喘急性发作和Arg16 beta（2）-受体多态性：按治疗分层的荟萃分析
2. Beta2-adrenergic receptor polymorphisms affect response to treatment in children with severe asthma exacerbations. [J] . Carroll CL, Stoltz P, Schramm CM, Chest: The Journal of Circulation, Respiration and Related Systems . 2009,第5期

机译：Beta2-肾上腺素能受体多态性影响严重哮喘加重患儿对治疗的反应。
3. Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. [J] . Wechsler ME, Kunselman SJ, Chinchilli V The Lancet . 2009,第9703期

机译：β2-肾上腺素能受体多态性对哮喘中长效β2激动剂反应的影响（大型试验）：一项基因型分层，随机，安慰剂对照，交叉试验。
4. The Effect of Theophylline in the Exacerbation of Childhood Asthma [C] . H. Odajima, H. Watanabe, T. Fujisawa Asia Pacific Congress of Allergology and Clinical Immunology . 2004

机译：茶碱在儿童哮喘加剧中的影响
5. The role of the beta-1,2-adrenergic and GRK5 receptor single-nucleotide-polymorphisms on the treatment of heart failure with beta-blockers. [D] . Rogers, Hobart Lee, Jr. 2010

机译：β-1,2-肾上腺素和GRK5受体单核苷酸多态性在使用β-受体阻滞剂治疗心力衰竭中的作用。
6. Childhood asthma exacerbations and the Arg-16 beta2 receptorpolymorphism: a meta-analysis stratified by treatment [O] . Steve Turner, Ben Francis, Susanne Vijverberg, -1

机译：儿童哮喘恶化和Arg-16 beta2受体多态性：按治疗分层的荟萃分析
7. Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment [O] . Turner, Steve, Francis, Ben, Vijverberg, Susanne, 2016

机译：儿童哮喘急性发作和Arg16 beta（2）-受体多态性：按治疗分层的荟萃分析

Childhood asthma exacerbations and the Arg16 beta(2)-receptor polymorphism: A meta-analysis stratified by treatment

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