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An analytical approach to neuronal connectivity

机译:神经元连通性的分析方法

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This paper describes how to analytically characterize the connectivity of neuromorphic networks taking into account the morphology of their elements. By assuming that all neurons have the same shape and are regularly distributed along a two-dimensional orthogonal lattice with parameter Delta, we obtain the exact number of connections and cycles of any length by applying convolutions and the respective spectral density derived from the adjacency matrix. It is shown that neuronal shape plays an important role in defining the spatial distribution of synapses in neuronal networks. In addition, we observe that neuromorphic networks typically present an interesting property where the pattern of connections is progressively shifted along the spatial domain for increasing connection lengths. This arises from the fact that the axon reference point usually does not coincide with the cell center of mass of neurons. Morphological measurements for characterization of the spatial distribution of connections, including the adjacency matrix spectral density and the lacunarity of the connections, are suggested and illustrated. We also show that Hopfield networks with connectivity defined by different neuronal morphologies, which are quantified by the analytical approach proposed herein, lead to distinct performances for associative recall, as measured by the overlap index. The potential of our approach is illustrated for digital images of real neuronal cells.
机译:本文介绍了如何分析神经形态网络的连通性,同时考虑到其元素的形态。通过假设所有神经元具有相同的形状,并沿着带有参数Delta的二维正交晶格规则地分布,我们可以通过应用卷积和从邻接矩阵得出的各个光谱密度来获得任意长度的连接和循环的精确数目。结果表明,神经元形状在定义神经元网络中突触的空间分布中起着重要作用。此外,我们观察到神经形态网络通常会表现出一种有趣的特性,其中连接的模式会沿着空间域逐渐移动以增加连接长度。这是由于轴突参考点通常与神经元的细胞质心不一致而引起的。建议并说明了用于表征连接空间分布的形态学测量,包括邻接矩阵光谱密度和连接的空隙度。我们还显示,具有通过不同神经元形态定义的连通性的Hopfield网络(通过本文中提出的分析方法进行了量化)导致了相关召回的不同性能,如重叠指数所测。对于真实的神经元细胞的数字图像,说明了我们方法的潜力。

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