There are currently an estimated 86 500 individuals living with HIV infection in the UK, one-quarter of whom are unaware, of their infection. Of the 6630 adults newly diagnosed in 2009, 52% had a CD4 count less than 350 x 10~6/L at the time of diagnosis, the recommended threshold at which antiretroviral therapy should be commenced. Thirty per cent were diagnosed with a CD4 count less than 200 x 10~6/L, which is indicative of severe immune deficiency and associated with a significantly higher risk of death in the first 3 months. Earlier diagnosis allows more timely initiation of therapy and is associated with a higher estimated life expectancy than for individuals started on treatment in late disease. Approximately one-quarter of all deaths in HIV-positive people are attributable to late diagnosis. Furthermore, earlier diagnosis has potential benefits to the wider public health. Knowledge of HIV infection is associated with behaviour change to reduce the risk of onward transmission.
展开▼
机译：目前，在英国，估计有86500例HIV感染者，其中四分之一不知道自己的感染情况。在2009年新诊断的6630名成年人中，有52％的人在诊断时CD4计数低于350 x 10〜6 / L，这是开始抗逆转录病毒治疗的推荐阈值。 30％的患者被诊断出CD4计数低于200 x 10〜6 / L，这表明存在严重的免疫缺陷，并且在头3个月中死亡的风险明显更高。较之在晚期疾病中开始治疗的患者，较早的诊断可以更及时地开始治疗，并具有更高的预期寿命。艾滋病毒呈阳性的人中约有四分之一的死亡归因于晚期诊断。此外，早期诊断对更广泛的公共卫生具有潜在的好处。感染艾滋病毒的知识与行为改变有关，以减少继续传播的风险。
展开▼
