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A forgotten founding father of the Pill: Ferdinand Peeters, MD

机译:一位被遗忘的创始之父:医学博士费迪南德·皮特斯(Ferdinand Peeters)

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摘要

Ferdinand Peeters, a practising gynaecologist from Turnhout, near Antwerp (Belgium), had a pivotal role in the development of a practical and viable modality of oral contraception, striking the balance between efficacy and an acceptably low incidence and severity of side effects. While, with regard to the origin of oral contraception, names like those of Pincus, Rock, and Djerassi come immediately to the fore, the work of Peeters has to a large extent faded from public memory. Still, it was Peeters who proposed to Schering AG in Berlin that a combination of 4 mg norethisterone acetate and 0.05 mg ethinylestradiol be used for ovulation suppression. He convinced the scientific staff of Schering of the potential benefits of what, after clinical trials, would finally emerge as Anovlar ?.
机译:来自比利时安特卫普附近特恩豪特(Turnhout)的妇科医生费迪南德·皮特斯(Ferdinand Peeters)在开发一种实用且可行的口服避孕方法中发挥了关键作用,在疗效与副作用的发生率和严重性之间达到了可接受的低点。关于口服避孕药的起源,像平克斯,洛克和杰拉西这样的名字很快就脱颖而出,而Peeters的工作在很大程度上已经从公众记忆中消失了。仍然是Peeters向柏林先灵(Schering AG)提议将4 mg乙酸炔诺酮和0.05 mg炔雌醇的组合用于排卵抑制。他说服先灵科学团队的潜在利益,经过临床试验,最终将成为Anovlar吗?

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