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An Integrative Cognitive-behavioral Approach for the Treatment of Type 2 Diabetes Mellitus: A Pilot Study

机译:综合认知-行为方式治疗2型糖尿病的临床研究

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Type 2 diabetes mellitus (T2DM) is a chronic illness with a multifactorial etiology, which includes psychophysiological and behavioral factors. Patients often do not achieve sufficient metabolic balance despite provision of maximal medical treatment. Numerous studies have demonstrated that psychologic processes play an important role in this balance. Most previous intervention studies do not address multiple risk factors simultaneously, within an integrative framework. The current study looked for. the effect of an integrative cognitive-behavioral intervention on T2DM patients by monitoring both metabolic control and psychologic state. A pilot study was conducted with 11 T2DM elderly patients who participated in an integrative interdisciplinary group intervention program. Participants were provided with nutritional instruction and stress-reduction techniques such as cognitive-behavioral skills, relaxation, and physical exercise. Baseline and postintervention comparisons showed a statistically significant reduction in lipids, glycosylated hemoglobin, total and low-density lipoprotein cholesterol, and in anxiety and depression in all participants. Future studies on larger groups of patients are needed to substantiate these preliminary findings and explore the mechanisms underlying the relationship between behavioral and biologic parameters in T2DM.
机译:2型糖尿病(T2DM)是一种具有多种病因的慢性疾病,包括心理生理和行为因素。尽管提供了最大的药物治疗,患者通常仍无法达到足够的代谢平衡。大量研究表明,心理过程在这种平衡中起着重要作用。以前的大多数干预研究都不能在一个综合框架内同时解决多个风险因素。当前的研究正在寻找。通过监测代谢控制和心理状态,综合性认知行为干预对T2DM患者的影响。对参加综合性跨学科干预计划的11名T2DM老年患者进行了一项初步研究。为参与者提供了营养指导和减轻压力的技术,例如认知行为技能,放松和体育锻炼。基线和干预后的比较显示所有参与者的脂类,糖基化血红蛋白,总和低密度脂蛋白胆固醇以及焦虑和抑郁的统计学降低。需要对更大范围的患者进行进一步的研究,以证实这些初步发现,并探索T2DM中行为和生物学参数之间关系的潜在机制。

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