SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION COMPRISING 5 - 4 - 2- (N - METHYL - N - (2 - PYRIDYL) AMINO) ETHOXY BENZYL THIAZOLIDINE - 2,4 - DIONE AND USE THEREOF IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF TYPE 2 DIABETES MELLITUS AND CONDITIONS ASSOCIATED WITH DIABETES MELLITUS

摘要

A method for the treatment of Type 2 diabetes mellitus and conditions associated with diabetes mellitus, which method comprises the administration to a human or non-human mammal in need thereof, of an effective non-toxic amount of an insulin sensitiser so as to provide a plasma concentration of the insulin sensitiser of at least a threshold level (the 'Threshold Plasma Concentration') from within the range of effective plasma levels of the insulin sensitiser, compositions for use in such method and methodology for determining plasma concentrations of active agent use in such methods.