Gastric Emptying in Subclinical Hypothyroidism

摘要

The aim of this study is to investigate solid-phase gastric emptying in patients with subclinical hypothyroidism and to compare it with healthy subjects. Twenty patients with a recently established diagnosis of subclinical hypothyroidism and 10 age-matched healthy subjects participated in this study. Gastric emptying half-time was calculated with solid food labeled with 250muCi ~(99m)Tc-sulfur colloid. There was no difference between serum free T_3 and T_4 values in both groups. Serum thyroid-stimulating hormone level was significantly higher in the subclinical hypothyroid group than in controls. Gastric emptying half-time was 123.94 ± 18.58 minutes in the subclinical hypothyroid group and 101.80 ± 25.56 minutes in the control group. These gastric emptying half-times were not different (P = 0.455). We suggest that in subclinical hypothyroidism, gastric emptying of solids is similar to that in age-matched healthy control subjects.