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Analysis of 3-d structure of sarcoplasmic reticular calcium pump

机译:肌浆网状钙泵的3维结构分析

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A research group of Prof. K. Toshima et al. at the Institute of Molecular Cytobiology, the University of Tokyo, have succeeded for the first time in the world in analyzing the 3-d structure of the calcium pump for sarcoplasmic reticular using beam lines of "Spring-8," large-sized radial ray equipment. By the analysis of the 3-d structure, it has become possible to clarify the junction of "phosphoramvan" where the motion of the pump is brought to a stop. As a result, it has become possible to promote the development of six types of medicines for myocardial infarction and similar diseases which are caused to happen when the pump is brought to a stop. Furthermore, it may become possible in the near future to develop a medicine that is effective for arresting the advancement of cancer.
机译:Toshima K.等人的研究小组。东京大学分子细胞生物学研究所的研究,是世界上首次成功使用大直径放射线“ Spring-8”的光束线分析了肌浆网状钙泵的3维结构设备。通过对3-d结构的分析,有可能弄清楚“ phosphoramvan”的接合处,在该处使泵的运动停止。结果,有可能促进开发六种类型的用于心肌梗塞和类似疾病的药物,这些药物在泵停止运转时会发生。此外,在不久的将来有可能开发出一种对阻止癌症进展有效的药物。

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