A 30-year-old African-American woman with a 5-year history of pernicious anemia diagnosed after a work-up for weakness and iron-deficiency anemia underwent a screening upper endoscopy. She denied nausea or vomiting, melana, hematemesis, diarrhea, palpitations, or flushing. Her family history was significant for adeno-carcinoma of the colon and stomach in a paternal grandmother. Upper endoscopy revealed a large sub-mucosal pedunculated mass that was reducible after passage through the pylorus, as well as multiple polypoid lesions along the greater curvature and posterior wall of the stomach. The duodenum was unremarkable.
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