DETERMINATION OF THE ABSOLUTE CONFIGURATION OF YESSOTOXIN, A POLYETHER COMPOUND IMPLICATED IN DIARRHETIC SHELLFISH POISONING, BY NMR SPECTROSCOPIC METHOD USING A CHIRAL ANISOTROPIC REAGENT, METHOXY-(2-NAPHTHYL)ACETIC ACID

摘要

The absolute configuration of yessotoxin (1), a potent diarrhetic toxin causative of shellfish poisoning, was determined by NMR-spectroscopy using a chiral anisotropic reagent, methoxy-(2-naphthyl)acetic acid (2NMA), which was applied to a monoacetate of bisdesulfated yessotoxin (3). Copyright (C) 1996 Elsevier Science Ltd [References: 14]