SYNTHESIS OF QUATERNARY AMINO ACIDS CONTAINING BETA,GAMMA- AS WELL AS GAMMA,DELTA-UNSATURATED SIDE CHAINS VIA CHELATE-ENOLATE CLAISEN REARRANGEMENT

摘要

Ester enolate Claisen rearrangement of chelated N-protected alpha,beta-unsaturated amino acid allylic esters results in a migration of the double bond and the formation of highly unsaturated amino acids in good yields and in a highly diastereoselective fashion. Copyright (C) 1996 Elsevier Science Ltd [References: 37]