CYCLOPEPTIDES FROM ASCIDIANS - TOTAL SYNTHESIS OF LISSOCLINAMIDE 4, AND A GENERAL STRATEGY FOR THE SYNTHESIS OF CHIRAL THIAZOLINE-CONTAINING MACROCYCLIC PEPTIDES

摘要

In the first synthesis of a chiral thiazoline-containing macrocyclic peptide, a total synthesis of lissoclinamide 4 2c, produced by the marine tunicate Lissoclinum patella, is described. [References: 18]