Insertions of silylated carbenoids into vinylzirconocene chlorides. A convergent route to silyl-substituted allylzirconium reagents

摘要

A convergent route to allylzirconocene reagents by insertion of silyl-substituted carbenoids LiCR(SiMe3)(Cl) into vinylzirconocene chlorides is reported. The product silylated allylzirconocenes react with aldehydes and ketones with high anti-selectivity to afford vinyl- (R=H) or allyl- (R=Me, Pr) silanes which may be converted into 4,5-trans-disubstitituted gamma-lactones and stereodefined dienes. (C) 1999 Elsevier Science Ltd. All rights reserved. [References: 33]