Indium-mediated, highly efficient and diastereoselective addition of cyclic secondary allylic bromides to carbonyl compounds

摘要

Indium-mediated addition of 3-bromocyclohexene and 3-bromocyclooctene to a variety of aromatic aldehydes and cyclohexanone proceeds smoothly with excellent syn diastereoselectivity to produce the corresponding cycloalkenyl substituted homoallylic alcohols in good to high yields. (C) 2000 Elsevier Science Ltd. All rights reserved. [References: 22]