Role of 5-aminosalicylate in preventing colorectal cancer.

摘要

To the Editor: We read the recent article published by Bernstein et al. (1) concerning the lack of efficiency of 5-aminosalicylates (5-ASA) in preventing colorectal cancer (CRC) in inflammatory bowel disease (IBD) with interest. Previous studies have shown conflicting results regarding any role of 5-ASA in chemoprophylaxis against CRC in IBD (2-5). This population-based study attempts to resolve this uncertainty but unfortunately has several shortcomings.