Falling rates of malaria among U.S. Military Service Members in Afghanistan substantiate findings of high compliance with daily chemoprophylaxis

摘要

Dear Sir: I read with interest the report by Brisson and Brisson that showed higher compliance among U.S. military service members in Afghanistan with daily as compared with weekly malaria chemoprophylaxis. By conventional wisdom these results appear counterintuitive, and they stand in contrast to earlier findings among civilian travelers and military personnel3 that suggest observed compliance should be higher with weekly dosing. Despite this, their findings of high compliance are substantiated by recent evidence of ecological association among U.S. military personnel in Afghanistan between falling rates of malaria and changes in chemoprophylaxis policy that now favor daily medications.