Studies towards the total synthesis of taxoids: a rapid entry into bicyclo[6.4.0]dodecane ring system. Part 2

摘要

We report a synthetic route that allows access into A-seco taxoid frameworks embodying the entire carbon skeleton and a large number of oxygen functionalities. The BC-subunit (-)-4 was constructed in five steps from (+)-3, through a step-efficient and stereocontrolled bond construction.