Palladium-catalyzed direct arylations of azoles with aryl silicon and tin reagents

摘要

Regioselective arylations of imidazoles, oxazoles, and thiazoles were achieved by palladium-catalyzed cross-coupling with trialkoxy(aryl)silanes or allyltriphenylstannane (see scheme). Addition of ligands or exclusion of moisture was not necessary to obtain C2-substituted azoles in high yields.