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Functional Outcomes and Complications in Patients With Bladder Cancer Undergoing Robotic-assisted Radical Cystectomy With Extracorporeal Indiana Pouch Continent Cutaneous Urinary Diversion

机译:膀胱癌行机器人辅助根治性膀胱切除术并进行体外印第安纳囊袋性尿路皮肤尿路转移的膀胱癌患者的功能结局和并发症

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To evaluate the functional outcomes and complications for patients with bladder cancer undergoing robotic-assisted laparoscopic radical cystectomy with Indiana pouch continent cutaneous urinary diversion.From February 2004 to March 2010, 34 patients underwent robotic-assisted laparoscopic radical cystectomy with Indiana pouch continent cutaneous urinary diversion reconstruction. After surgery, the complications were identified, categorized, and graded using an established 5-grade modification of the original Clavien grading system, and continence was assessed. Descriptive statistics were used in evaluating the outcomes. Fischer's exact test was used in the comparison of early and late Clavien grade III complications.Overall, 175 (123 early and 52 late) complications after surgery were reported in 32 (94%) of 34 patients. Within 90 days of surgery, 31 (91%) of 34 patients experienced ^1 early complication. Of 34 patients, 15 (44%) reported >1 late complications (>90 days). Most (85% and 69%, respectively) early and late complications were graded as minor (grade II or less). Fewer patients with early complications required an additional intervention (grade III) compared with patients with late complications (14% vs 31%; P = .116). The most common complication in both intervals was infection, reported in 22% and 37% of patients with early and late complications, respectively. The continence data for 31 patients at a mean follow-up of 20.1 months (median 12.0) showed that all but 1 patient (97%) had daytime and nighttime continence. Patients undergoing robotic-assisted laparoscopic radical cystectomy with Indiana pouch continent cutaneous urinary diversion reconstruction have comparable complication rates and functional outcomes compared with patients in the open series.
机译:为了评估接受机器人辅助腹腔镜根治性膀胱切除并伴有印第安纳囊袋大陆行皮肤导尿术的膀胱癌患者的功能结局和并发症.2004年2月至2010年3月,有34例患者接受了机器人辅助腹腔镜根治性膀胱切除术并进行了印第安纳囊袋大陆行皮肤导尿重建。手术后,使用已建立的原始Clavien分级系统的5级修改对并发症进行识别,分类和分级,并评估节制。描述性统计用于评估结果。 Fischer的精确检验用于比较Clavien III级早期和晚期并发症的发生情况.34例患者中有32例(94%)报告了175例(123例早期和52例晚期)并发症。在手术的90天之内,34例患者中有31例(91%)经历了^ 1早期并发症。在34例患者中,有15例(44%)报告晚期并发症(> 90天)> 1。大多数早期和晚期并发症(分别为85%和69%)被定为轻微(II级或以下)。与晚期并发症患者相比,发生早期并发症的患者较少(III级)(14%vs 31%; P = .116)。两种间隔中最常见的并发症是感染,分别有22%和37%的早期和晚期并发症患者发生感染。平均随访20.1个月(中位数12.0)的31例患者的尿失禁数据显示,除1例患者(97%)外,其他所有患儿均具有白天和夜间的尿失禁。与开放系列患者相比,接受机械手辅助腹腔镜根治性膀胱切除术并进行印第安纳州小袋大陆皮肤尿路改道手术的患者具有相当的并发症发生率和功能结局。

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