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The Clinical Spectrum of the Presenting Signs and Symptoms of Anterior Urethral Stricture: Detailed Analysis of a Single Institutional Cohort

机译:前尿道狭窄的表现体征和症状的临床范围:单个机构队列的详细分析

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摘要

To accurately delineate the presentation of anterior urethrai stricture in an economically developed patient cohort. It is widely assumed that patients with urethral stricture typically present with lower urinary tract symptoms (LUTS). There is a paucity of data examining this assumption. With no uniformly accepted clinical definition or measure of treatment success, a clear clinical description of urethral stricture is important.Retrospective detailed analysis was performed on 611 patients presenting with anterior urethral stricture from July 2004 to June 2010. Both the presenting complaint and associated signs and symptoms were classified according to one of 10 clinical categories.The most common presenting complaint was LUTS typical of those found on the American Urological Association-Symptom Score (54.3%) and another 23.4% of patients presented initially with acute urinary retention (AUR). Symptoms other than LUTS or urinary retention accounted for 22.3% of presenting complaints. In addition, 22.9% of patients had genitourinary pain, 50.7% of patients required emergent urologic treatment, and 7.4% of patients presented with renal insufficiency or urethral abscessecrotizing fasciitis directly related to urethral stricture.Although many patients with urethral stricture present initially with LUTS or AUR, almost one quarter of patients have a different presenting complaint. Defining successful treatment of anterior urethral stricture should include more than improvement in LUTS or absence of urinary retention. Urethral stricture is not just a "quality of life" condition because >50% of patients require emergent treatment and 7.4% have a life-threatening condition directly related to the stricture.
机译:为了准确地描述经济发达的患者队列中前尿道狭窄的表现。人们普遍认为患有尿道狭窄的患者通常会出现下尿路症状(LUTS)。缺乏数据检查该假设。由于尚无统一的临床定义或治疗成功的方法,因此对尿道狭窄的明确临床描述很重要。2004年7月至2010年6月对611例前尿道狭窄患者进行了回顾性详细分析。根据10个临床类别之一对症状进行分类。最常见的主诉是美国泌尿科协会症状评分(54.3%)中典型的LUTS,另外23.4%的患者最初表现为急性尿retention留(AUR)。除了LUTS或尿retention留以外的其他症状占提出投诉的22.3%。此外,有22.9%的患者患有泌尿生殖系统疼痛,有50.7%的患者需要急诊泌尿外科治疗,以及7.4%的肾功能不全或尿道脓肿/坏死性筋膜炎患者与尿道狭窄直接相关。 LUTS或AUR,几乎四分之一的患者有不同的主诉。定义成功的前尿道狭窄治疗方法应包括改善LUTS或不存在尿absence留。尿道狭窄不仅是一种“生活质量”状况,因为> 50%的患者需要紧急治疗,而7.4%的病人的生命状况与狭窄直接相关。

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