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Predictors of inguinal hernia after radical prostatectomy.

机译:前列腺癌根治术后腹股沟疝的预测指标。

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OBJECTIVES: To determine the significant independent predictors of inguinal hernia development after radical prostatectomy (RP) so that prophylactic measures can be undertaken in those at increased risk. Although inguinal hernia is a recognized complication after RP, the risk factors have not been well elucidated. METHODS: From January 1999 to June 2007, 4592 consecutive patients underwent open retropubic RP or laparoscopic RP without previous radiotherapy. The median follow-up was 36.9 months (interquartile range 20.3, 60.6). Comorbidities were recorded, as well as the occurrence of inguinal hernia, wound infection, and bladder neck contracture. Cox proportional hazards analysis was performed for the predictors of inguinal hernia after RP on multivariate analysis. RESULTS: Inguinal hernia developed after RP in 68 men (1.5%) men at a median follow-up of 7.9 months (interquartile range 4.3, 18.1). The laterality was bilateral in 7, right in 27, left in 24, and not documented in 10 patients. The significant independent predictors of inguinal hernia included age (hazard ratio [HR] 1.05, 95% confidence interval [CI] 1.01-1.09, P = .016), body mass index (HR 0.91, 95% CI 0.85-0.98, P = .011), history of inguinal hernia repair (HR 3.9, 95% CI 1.8-8.2, P <.001), and bladder neck contracture (HR 2.8, 95% CI 1.3-5.9, P = .007) but not the RP approach (HR 1.08, 95% CI 0.60-1.96, P = .80 for laparoscopic RP vs retropubic RP). CONCLUSIONS: The results of our study have indicated that older patients, thinner patients, those with previous inguinal hernia repair, and those developing bladder neck contracture are at increased risk of developing an inguinal hernia. These factors might identify a subset for whom evaluation for subclinical hernia might allow prophylactic inguinal hernia repair at RP.
机译:目的:确定根治性前列腺切除术(RP)后腹股沟疝发生的重要独立预测因素,以便对高危人群采取预防措施。尽管腹股沟疝是RP后公认的并发症,但尚未充分阐明危险因素。方法:从1999年1月至2007年6月,连续4592例患者接受了开放性耻骨后RP或腹腔镜RP,而未进行过放射治疗。中位随访时间为36.9个月(四分位间距为20.3、60.6)。记录合并症,以及腹股沟疝,伤口感染和膀胱颈挛缩的发生。对多因素分析中RP后腹股沟疝的预测因素进行Cox比例风险分析。结果:68名男性(1.5%)的男性在RP后出现腹股沟疝,中位随访时间为7.9个月(四分位间距为4.3、18.1)。两侧为7侧,右侧为27侧,左侧为24侧,没有记录10例患者。腹股沟疝的重要独立预测因素包括年龄(危险比[HR] 1.05,95%置信区间[CI] 1.01-1.09,P = .016),体重指数(HR 0.91,95%CI 0.85-0.98,P = .011),腹股沟疝修补术史(HR 3.9,95%CI 1.8-8.2,P <.001)和膀胱颈挛缩(HR 2.8,95%CI 1.3-5.9,P = .007),但非RP方法(HR 1.08,95%CI 0.60-1.96,腹腔镜RP与耻骨后RP的P = 0.80)。结论:我们的研究结果表明,年龄较大的患者,较瘦的患者,先前腹股沟疝修补的患者以及发展成膀胱颈挛缩的患者患腹股沟疝的风险增加。这些因素可能会确定亚临床疝的评估可以允许在RP进行预防性腹股沟疝修补的子集。

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