Reply to Letter-to-the-Editor: Prevalence of Pelvic Floor Dysfunction in Patients With Interstitial Cystitis. Urology 71:1231, 2008

摘要

We appreciate the thoughtful comments regarding our paper on pelvic floor dysfunction in patients with interstitial cystitis (IC). We agree that many etiologies may be involved in the pain associated with IC and the bladder may be an "innocent bystander" in a more diffuse process. Many patients with IC suffer from other co-morbidities such as fibromyalgia, chronic fatigue syndrome, vulvo-dynla, and irritable bowel syndrome.1 It is doubtful that pudendal neuropathy alone would account for all of these co-morbidities. Certainly, diffuse hypersensitivity or nerve upregulation may be a central cause of pain and other co-morbidities associated with IC/painful bladder syndrome.