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Evaluation of long-term thermal injury using cautery during nerve sparing robotic prostatectomy.

机译:保留神经的机器人前列腺切除术中使用烧灼术评估长期热损伤。

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OBJECTIVE: In our initial 125 cases, we used cautery during preservation of the neurovascular bundles (NVBs). We previously reported the short-term benefit of a cautery-free versus cautery technique. To assess long-term consequences of cautery, we report 2-year potency outcomes for these robot-assisted laparoscopic radical prostatectomies (RLP). METHODS: Between June 2002 and February 2004, 125 consecutive patients underwent RLP by 1 surgeon. All data were entered prospectively into an electronic database. In cases 1 to 15, the vascular pedicle and nerve were dissected with monopolar cautery. In cases 16 to 125, the dissection used bipolar cautery and scissors. Preoperatively, 42 met inclusion criteria: age younger than 66 years, International Index of Erectile Function (IIEF-5) of 22 to 25 and uni (12) or bilateral (35) nerve sparing. Postoperatively all patients were encouraged to use 5-PDE inhibitors. Potency was assessed by self-administered validated questionnaires. RESULTS: Four were excluded because of treatment intervention (3) or refusal to follow-up (1). Thirty-eight have follow-up data of 24 or more months. At 3, 9, and 15 months only 3 of 36 (8.3%), 5 of 34 (14.7%), and 16 of 37 (43.2%) were potent. However at 24+ months, 5 of 10 (50%) of unilateral and 19 of 28 bilateral nerve-sparing (68%) were potent with an average IIEF-5 of 18.4 and erectile firmness of 75% to 100% of baseline. CONCLUSION: These findings suggest that in addition to other injury, thermal injury to the NVB is dense with very low recovery rates in the first 12 to 18 months. However, with nearly two-thirds ultimately reporting potency return, these injuries are generally not permanent and recovery approaches 75% to 100% of baseline.
机译:目的:在我们最初的125例患者中,我们在保存神经血管束(NVB)时使用了烧灼术。我们之前曾报道过无电灼术与电灼术相比的短期收益。为了评估电烙术的长期后果,我们报告了这些机器人辅助的腹腔镜根治性前列腺切除术(RLP)的2年疗效。方法:2002年6月至2004年2月,由1位外科医生连续对125例患者进行了RLP。所有数据均已预先输入电子数据库中。在病例1至15中,通过单极电灼切开血管蒂和神经。在病例16至125中,解剖采用双极电灼和剪刀。术前有42位患者符合纳入标准:年龄小于66岁,国际勃起功能指数(IIEF-5)为22至25,单侧(12)或双侧(35)保留神经。术后鼓励所有患者使用5-PDE抑制剂。效能通过自我管理的有效问卷进行评估。结果:因治疗干预(3)或拒绝随访(1)而被排除在外。 38个具有24个月或更长时间的随访数据。在第3、9和15个月中,只有36个中的3个(8.3%),34个中的5个(14.7%)和37个中的16个(43.2%)有效。然而,在24个多月时,单侧10个中的5个(50%)和28个双侧神经保留中的19个(68%)有效,平均IIEF-5为18.4,勃起硬度为基线的75%至100%。结论:这些发现表明,除了其他损伤外,NVB的热损伤较重,在最初的12至18个月内恢复率非常低。但是,最终有将近三分之二的人报告了有力回报,这些伤害通常不是永久性的,恢复率接近基线的75%至100%。

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