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Open prostatectomy is still a valid option for large prostates: a high-volume, single-center experience.

机译:对于大型前列腺癌,开放式前列腺切除术仍然是一种有效的选择:大量,单中心的经验。

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OBJECTIVES: To evaluate, in a retrospective, single-center trial, our open prostatectomy outcomes and complications in the past 12 years to emphasize the feasibility of open prostatectomy for large prostates. METHODS: A total of 1193 patients underwent open prostatectomy from 1995 to 2007. We retrospectively analyzed the data from 664 patients who had preoperative, operative, and postoperative data available. RESULTS: The mean patient age was 67.5 years (range 52-86). The mean preoperative prostate-specific antigen value was 9.6 ng/mL (range 1.65-45.6). The mean prostatic weight was 88.7 g (range 45-324) and was significantly different for the 1995-2001 and 2002-2007 groups (73.6 vs 98.2 g, respectively). Of the 664 patients, 208 (31%) had had an indwelling catheter before surgery. The average International Prostate Symptom Score was 21.7 (range 13-32) preoperatively and 10.6 (range 8-18) postoperatively (P .005). The average hospitalization was 6.74 days (range 4-14). Blood transfusion was required in 12.7% of the patients either intraoperatively or postoperatively. Postoperatively, 82 patients (12.3%) had urinary tract infections, 22 (3.2%) had bladder neck obstruction, 5 (0.7%) had urinary incontinence, and 15 (2.3%) had a ureteral meatus stricture. CONCLUSIONS: Open prostatectomy is a feasible treatment option for patients with a large prostate and also for patients with additional bladder pathologic findings such as bladder calculi or diverticula for whom endoscopic treatment modalities are not appropriate. Consequently, open prostatectomy is still the primary option for patients with a prostate greater than 100 cm(3) and preserves its importance in urology practice, even in the presence of endoscopic innovations.
机译:目的:在一项回顾性单中心试验中,评估过去12年间我们开放式前列腺切除术的结果和并发症,以强调开放式前列腺切除术在大型前列腺癌中的可行性。方法:从1995年至2007年,共有1193例患者接受了开放式前列腺切除术。我们回顾性分析了664例术前,术中和术后患者的数据。结果:平均患者年龄为67.5岁(范围52-86)。术前前列腺特异性抗原的平均值为9.6 ng / mL(范围1.65-45.6)。平均前列腺重量为88.7 g(范围45-324),在1995-2001年和2002-2007年组中有显着差异(分别为73.6和98.2 g)。在664例患者中,有208例(31%)在手术前有留置导管。术前平均国际前列腺症状评分为21.7(范围13-32),术后平均10.6(范围8-18)(P <.005)。平均住院时间为6.74天(范围4-14)。术中或术后需要输血的患者占12.7%。术后有82例(12.3%)患有尿路感染,22例(3.2%)患有膀胱颈阻塞,5例(0.7%)患有尿失禁,15例(2.3%)患有输尿管狭窄。结论:对于前列腺大的患者以及其他膀胱病理学发现如膀胱结石或憩室不适合内镜治疗的患者,开放式前列腺切除术是可行的治疗选择。因此,对于前列腺大于100 cm(3)的患者,开放式前列腺切除术仍然是主要选择,即使在存在内窥镜创新的情况下,开放式前列腺切除术仍在泌尿外科实践中保持着重要地位。

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