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Robotic ureterolysis for relief of ureteral obstruction from retroperitoneal fibrosis.

机译:机器人输尿管溶栓术可缓解腹膜后纤维化引起的输尿管阻塞。

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OBJECTIVE: To review our experience with robotic surgery for the management of retroperitoneal fibrosis (RPF) with ureteral obstruction. Ureteral obstruction is common in retroperitoneal fibrosis RPF. METHODS: Since April 2006, 21 patients have presented to our institution with ureteral obstruction, apparently from RPF. All underwent robotic biopsy. If frozen pathology reveals malignancy, is equivocal, and/or the fibrotic reaction is extensive, we stent the obstructed side(s) and await final pathology. If RPF is confirmed, medical therapy is initiated to relieve obstruction; failures receive salvage ureterolysis. Lymphomas are referred to medical oncology. If frozen pathology demonstrates RPF, immediate ureterolysis is performed, if technically feasible. Ureterolysis is not performed for uninvolved contralateral systems. We reviewed data with institutional review board approval. RESULTS: Of 21 patients, 3 were diagnosed with lymphoma and 18 with RPF. Seventeen patients (21 renal units) with RPF received robotic ureterolysis (11 primary, 6 salvage); the other patient died of trauma before intervention. The only perioperative complication, an enterocutaneous fistula, required bowel resection. Three patients required a secondary procedure to relieve obstruction. At a mean follow-up of 20.5 months, no renal unit has evidence of obstruction, and all patients have improved or resolved symptoms. Furthermore, none of the 13 patients who underwent a unilateral ureterolysis have had disease progression to the contralateral side. CONCLUSIONS: Robotic ureterolysis can be performed with minimal morbidity and provides durable success rates for relief of symptoms and obstruction in RPF. Biopsy remains integral to ruling out lymphoma. Empiric contralateral ureterolysis may not be necessary.
机译:目的:回顾我们在机器人手术中治疗输尿管梗阻性腹膜后纤维化(RPF)的经验。输尿管梗阻在腹膜后纤维化RPF中很常见。方法:自2006年4月以来,有21例患者因输尿管阻塞而出现输尿管梗阻。所有患者均进行了机器人活检。如果冰冻病理显示恶性,模棱两可,和/或纤维化反应广泛,我们将梗阻的一侧置入支架,等待最终病理。如果确认RPF,则开始药物治疗以缓解阻塞;失败者会抢救输尿管。淋巴瘤被称为医学肿瘤学。如果冷冻病理证实为RPF,则在技术上可行的情况下,应立即进行输尿管溶解术。不介入的对侧系统不进行输尿管溶解。我们在机构审查委员会的批准下审查了数据。结果:21例患者中,3例被诊断为淋巴瘤,18例被诊断为RPF。 17例RPF患者(21个肾单位)接受了机器人输尿管溶栓术(11例原发性,6例抢救);另一例患者在干预之前死于创伤。唯一的围手术期并发症是肠胃瘘,需要行肠切除术。三名患者需要第二次手术以缓解阻塞。平均随访20.5个月,没有肾脏单位有阻塞的迹象,所有患者的症状均得到改善或缓解。此外,接受单侧输尿管溶解术的13例患者中,没有一例进展到对侧。结论:机器人输尿管溶栓术的发病率极低,为RPF缓解症状和阻塞提供了持久的成功率。活检仍是排除淋巴瘤必不可少的部分。可能不需要经验性对侧输尿管溶解术。

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